Article
Linkage between rheumatoid arthritis susceptibility and the presence of HLA-DR4 and DR beta allelic third hypervariable region sequences in southern Chinese persons.
Arthritis and rheumatism - 1 Feb 1992
Seglias J, Li E K, Cohen M G, Wong R W, Potter P K, So A K
Abstract excerpt
OBJECTIVE: To analyze HLA-DR and DQ associations with rheumatoid arthritis (RA) in patients from southern China. METHODS: In 66 patients and 45 controls, restriction fragment length polymorphism studies were performed using DRB, DQA, and DQB probes, and DRB allele-specific typing of polymerase ch...
Topics
- Alleles
- Amino Acid Sequence
- Arthritis, Rheumatoid
- China
- Disease Susceptibility
- Gene Amplification
- Genetic Linkage
- HLA-DR Antigens
- Humans
- Hybridization, Genetic
- Molecular Sequence Data
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length