Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Linkage between rheumatoid arthritis susceptibility and the presence of HLA-DR4 and DR beta allelic third hypervariable region sequences in southern Chinese persons.

Arthritis and rheumatism - 1 Feb 1992

Seglias J, Li E K, Cohen M G, Wong R W, Potter P K, So A K

Abstract excerpt

OBJECTIVE: To analyze HLA-DR and DQ associations with rheumatoid arthritis (RA) in patients from southern China. METHODS: In 66 patients and 45 controls, restriction fragment length polymorphism studies were performed using DRB, DQA, and DQB probes, and DRB allele-specific typing of polymerase chain reaction-amplified DRB DNA: RESULTS: The frequency of HLA-DR4 was significantly increased among RA patients (42.4%...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Amino Acid Sequence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Disease Susceptibility

Share to Genetic Linkage

Share to HLA-DR Antigens

Share to Molecular Sequence Data

Share to Polymerase Chain Reaction

Share to Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 1346498
DOI: 10.1002/art.1780350207

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Linkage between rheumatoid arthritis susceptibility and the presence of HLA-DR4 and DR beta allelic third hypervariable region sequences in southern Chinese persons.PMID 1346498Read ↗

HLA-DRB1 alleles genotyping in patients with rheumatoid arthritis in Chinese.Semantic proximity Read ↗

The association of HLA-DRB1 alleles with rheumatoid arthritis in the Chinese Shantou population: a follow-up study.Semantic proximity Read ↗

HLA-DRB1 genotyping in patients with rheumatoid arthritis in Taiwan.Semantic proximity Read ↗

Meta-analysis of the association of HLA-DRB1 with rheumatoid arthritis in Chinese populations.Semantic proximity Read ↗

[The molecular basis of HLA DR4 alleles associated with rheumatoid arthritis in a Chinese population].Semantic proximity Read ↗

Influence of HLA Class II Alleles and DRB1-DQB1 Haplotypes on Rheumatoid Arthritis Susceptibility and Autoantibody Status in the Chinese Han Population.Semantic proximity Read ↗

Relationship between autoimmune hepatitis and HLA-DR4 and DRbeta allelic sequences in the third hypervariable region in Chinese.Semantic proximity Read ↗

[HLA-DRB1 alleles genotyping in patients with rheumatoid arthritis in Chinese].Semantic proximity Read ↗

[DNA typing for HLA-DR and HLA-DQ alleles in Chinese patients with rheumatoid arthritis].Semantic proximity Read ↗

Association of specific amino acid sequence of HLA-DR with rheumatoid arthritis in Koreans and its diagnostic value.Semantic proximity Read ↗

HLA-DRB1 shared epitope-dependent DR-DQ haplotypes are associated with both anti-CCP-positive and -negative rheumatoid arthritis in Chinese Han.Semantic proximity Read ↗

Rheumatoid arthritis in southern Spain: toward elucidation of a unifying role of the HLA class II region in disease predisposition.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.