Article
Defects of mitochondrial DNA.
Brain pathology (Zurich, Switzerland) - 1 Apr 1992
Zeviani M, Antozzi C
Abstract excerpt
In the past few years several syndromes have been associated with lesions of the human mitochondrial DNA. MtDNA is a small, circular extra-nuclear chromosome encoding essential components of the respiratory chain. MtDNA-related syndromes can be divided into two groups: mitochondrial encephalomyop...
Topics
- DNA, Mitochondrial
- Humans
- Kearns-Sayre Syndrome
- MELAS Syndrome
- MERRF Syndrome
- Mitochondrial Encephalomyopathies
- Mutation
- Ophthalmoplegia, Chronic Progressive External
- Optic Atrophies, Hereditary
- Point Mutation