Article
Mitochondrial encephalomyopathies.
Archives of neurology - 1 Nov 1993
DiMauro S, Moraes C T
Abstract excerpt
Mitochondrial diseases are uniquely interesting from a genetic point of view because mitochondria contain their own DNA (mtDNA) and are capable of synthesizing a small but vital set of proteins, all of which are components of respiratory chain complexes. Numerous mutations in mtDNA have been desc...
Topics
- Chromosome Deletion
- Cytochrome-c Oxidase Deficiency
- DNA
- DNA Replication
- DNA, Mitochondrial
- Electron Transport Complex II
- Electron Transport Complex IV
- Humans
- MELAS Syndrome
- MERRF Syndrome
- Mitochondrial Encephalomyopathies
- Mitosis
- Multienzyme Complexes
- Mutation
- NAD(P)H Dehydrogenase (Quinone)
- Optic Atrophies, Hereditary
- Oxidoreductases
- Point Mutation