Article
PAX8, a human paired box gene: isolation and expression in developing thyroid, kidney and Wilms’ tumors
1 Nov 1992
Abstract excerpt
Recent evidence indicates a crucial role for paired box genes in mouse and human embryogenesis. The murine Pax8 gene encodes a sequence-specific transcription factor and is expressed in the developing secretory system as well as in the developing and adult thyroid. This restricted expression pattern suggested involvement of the Pax8 gene in the morphogenesis of the above organs and prompted us to investigate the...
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