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Article

Simian virus 40 minichromosomes as targets for retroviral integration in vivo.

1 Oct 1992

Abstract excerpt

We present a method for studying multiple retroviral integration events into a small DNA target in vivo. Episomal simian virus 40 (SV40) genomes established by infection of CV-1 cells served as integration targets during subsequent infection with murine leukemia virus (MLV). Using a PCR-based assay for the abundance and distribution of integration events, nonrandom integration of MLV DNA into SV40 DNA is...

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PMID: 1329090
DOI: 10.1073/pnas.89.19.9237

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