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Article

Human cytomegalovirus-derived protein UL18 alters the phenotype and function of monocyte-derived dendritic cells.

Journal of leukocyte biology - 1 Jan 2008

Wagner Claudia S, Walther-Jallow Lilian, Buentke Eva, Ljunggren Hans-Gustaf, Achour Adnane, Chambers Benedict J

Abstract excerpt

Human cytomegalovirus (HCMV) encodes the MHC class I-like molecule UL18, which binds with high affinity to the leukocyte Ig-like receptor-1 (LIR-1), an inhibitory receptor commonly expressed on myeloid cells and subsets of NK and T cells. The exact role of UL18 is not known, in particular in relation to its proposed role in HCMV immune escape. Given the ubiquitous expression of LIR-1 on dendritic cells (DCs), we...

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PMID: 17898320
DOI: 10.1189/jlb.0307181

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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