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Article

Unique, Diverged, and Conserved Mitochondrial Functions Influencing Candida albicans Respiration

24 Jun 2019

Abstract excerpt

Candida albicans is an opportunistic fungal pathogen of major clinical concern. The virulence of this pathogen is intimately intertwined with its metabolic behavior, and mitochondria have a central role in that metabolism. Mitochondria have undergone many evolutionary changes, which include lineage-specific adaptations in association with their eukaryotic host. Seven lineage-specific genes required for electron...

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PMID: 31239372
DOI: 10.1128/mbio.00300-19

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