Article
Saccharomyces cerevisiae sec59 cells are deficient in dolichol kinase activity.
Proceedings of the National Academy of Sciences of the United States of America - 1 Aug 1992
Heller L, Orlean P, Adair W L
Abstract excerpt
The temperature-sensitive Saccharomyces cerevisiae mutant sec59 accumulates inactive and incompletely glycosylated protein precursors in its endoplasmic reticulum at the restrictive temperature. O-mannosylation and glycosyl phosphatidylinositol membrane anchoring of protein are also abolished, co...
Topics
- Dimethylallyltranstransferase
- Dolichol Phosphates
- Models, Biological
- Mutation
- Phosphoric Monoester Hydrolases
- Phosphotransferases
- Phosphotransferases (Alcohol Group Acceptor)
- Pyrophosphatases
- Saccharomyces cerevisiae
- Species Specificity
- Temperature