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Article

Genetic recombination between malignant hyperthermia and calcium release channel in skeletal muscle.

Clinical genetics - 1 May 1992

Fagerlund T, Islander G, Ranklev E, Harbitz I, Hauge J G, Møkleby E, Berg K

Abstract excerpt

Absolute linkage between the gene, on chromosome 19, for the calcium release channel (CRC) of the sarcoplasmic reticulum in skeletal muscle and malignant hyperthermia (MH) has been reported by other workers. In the present study of three Swedish Families informative with respect to this linkage relationship, definite recombinants were found in two families. We conclude that mutations in other genes than the CRC...

Topics

Alleles
Calcium Channels
Chromosomes, Human, Pair 19
Female
Genetic Linkage
Humans
Male
Malignant Hyperthermia
Muscles
Pedigree
Phenotype
Recombination, Genetic

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PMID: 1318804

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1318804-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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