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Article

Mapping of a further malignant hyperthermia susceptibility locus to chromosome 3q13.1.

American journal of human genetics - 1 Mar 1995

Sudbrak R, Procaccio V, Klausnitzer M, Curran J L, Monsieurs K, van Broeckhoven C, Ellis R, Heyetens L, Hartung E J, Kozak-Ribbens G

Abstract excerpt

Malignant hyperthermia (MH) is a potentially lethal pharmacogenetic disease for which MH susceptibility (MHS) is transmitted as an autosomal dominant trait. A potentially life-threatening MH crisis is triggered by exposure to commonly used inhalational anesthetics and depolarizing muscle relaxants. The first malignant hyperthermia susceptibility locus (MHS1) was identified on human chromosome 19q13.1, and...

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Source

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Identifiers

PMID: 7887423
PMCID: PMC1801161

Genes

RYR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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Mapping of a further malignant hyperthermia susceptibility locus to chromosome 3q13.1.PMID 7887423Read ↗

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