Article
Analysis of the mutant proBA operon from a proline-producing strain of Serratia marcescens.
Journal of general microbiology - 1 Apr 1992
Omori K, Suzuki S, Imai Y, Komatsubara S
Abstract excerpt
The nucleotide sequence of the proBA operon from a proline-hyperproducing mutant of Serratia marcescens was determined. Two base substitutions were found: one in the proB structural gene, coding for gamma-glutamyl kinase (GK), and a second one in the promoter region of the operon. The former base substitution led to a change of the predicted amino acid at position 117 from an alanine to a valine in GK. This...
Topics
- Amino Acid Sequence
- Base Sequence
- Cloning, Molecular
- Drug Resistance, Microbial
- Gene Expression Regulation
- Genes, Bacterial
- Genetic Vectors
- Molecular Sequence Data
- Mutation
- Operon
- Phosphotransferases
