Article
Induction of allogeneic tumour- and lymphokine-activated lymphocytes against hepatocellular carcinoma.
Journal of gastroenterology and hepatology - 1 Jan 2000
Yasumura S, Higuchi K, Hioki O, Okada K, Tsukishiro T, Tsuchida T, Miyagiwa M, Nambu S, Yasuyama T, Inoue K
Abstract excerpt
For clinical application of adoptive immunotherapy against hepatocellular carcinoma (HCC), it is not easy to prepare tumour specific effector cells such as cytotoxic T lymphocytes (CTL). To induce potent and broad-spectrum effectors, allogeneic cultured hepatoma cell lines (JHH-4 and HuH-6) were used as stimulators of peripheral blood lymphocytes (PBL) instead of autologous HCC cells. Allogeneic tumour- and...
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