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Article

Inhibition of herpes simplex virus production in vitro by cyclosporin A.

Archives of virology - 1 Jan 1992

Vahlne A, Larsson P A, Horal P, Ahlmén J, Svennerholm B, Gronowitz J S, Olofsson S

Abstract excerpt

Nontoxic concentrations of Cyclosporin A (CyA) dose-dependently inhibited herpes simplex virus (HSV) production in resting monkey kidney cells. The block was at the step of virus DNA synthesis as assessed by [3H]thymidine incorporation and by dot blot hybridization of infected cell DNA using a cloned 32P-labelled HSV DNA fragment (BamHI X) as probe. This was further supported by analysis of HSV protein synthesis...

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Identifiers

PMID: 1309645
DOI: 10.1007/BF01321118

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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