Article
The virulence plasmid does not contribute to growth of Salmonella in cultured murine macrophages.
Microbial pathogenesis - 1 Oct 1992
Riikonen P, Mäkelä P H, Saarilahti H, Sukupolvi S, Taira S, Rhen M
Abstract excerpt
The virulence plasmid, characteristic of many serovars of Salmonella sp., and specifically its spv genes, promote intracellular growth of the bacteria in the liver and spleen and are essential for the virulence of these Salmonella serovars in the mouse. In an attempt to establish an in vitro mode...
Topics
- Animals
- Cells, Cultured
- Female
- Genetic Predisposition to Disease
- Interferon-gamma
- Lipopolysaccharides
- Macrophage Activation
- Macrophages
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C3H
- Mice, Inbred C57BL
- Mice, Inbred CBA
- Plasmids
- Recombinant Proteins
- Salmonella
- Virulence