Article
Acquisition of heat shock tolerance by regulation of intracellular redox states.
Biochimica et biophysica acta - 23 Sept 2003
Ueom Jeonghoon, Kwon Soonhyun, Kim Sunhee, Chae Youngkee, Lee Kyunghee
Abstract excerpt
In the yeast Saccharomyces cerevisiae, a mild heat treatment strongly induces Hsp104p which provides acquisition of thermotolerance. The mechanism by which Hsp104p protects cells from the severe heat shock has not yet been completely elucidated. In this study, a pivotal role of Hsp104p as an efficient scavenger of the reactive oxygen species (ROS) is investigated. In our previous study, we reported that Hsp104p...
Topics
- Cell Survival
- Cells, Cultured
- Fluoresceins
- Free Radical Scavengers
- Glutathione
- Heat-Shock Proteins
- Heat-Shock Response
- Hydrogen Peroxide
- Intracellular Fluid
- Mutation
- Oxidation-Reduction
- Oxidative Stress
- Reactive Oxygen Species
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Vitamin K 3
- ras Proteins