Article
Thermosensitive phenotype of yeast mutant lacking thioredoxin peroxidase.
Archives of biochemistry and biophysics - 1 Nov 1998
Lee S M, Park J W
Abstract excerpt
A soluble protein from Saccharomyces cerevisiae specifically provides protection against a thiol-containing oxidation system but not against an oxidation system without thiol. This 25-kDa protein acts as a peroxidase but requires a NADPH-dependent thioredoxin system or a thiol-containing intermediate, and was thus named thioredoxin peroxidase (TPx). The protective role of TPx in the cellular defense against heat...
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