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Article

The role of pathogenic DJ-1 mutations in Parkinson's disease.

Annals of neurology - 1 Sept 2003

Abou-Sleiman Patrick M, Healy Daniel G, Quinn Niall, Lees Andrew J, Wood Nicholas W

Abstract excerpt

Mutations in DJ-1 (PARK7) have been reported in two consanguineous families with young-onset Parkinson's disease (YOPD). This study aims to confirm the presence of pathogenic DJ-1 mutations and determine their contribution in young-onset and more typical later onset Parkinson's disease (PD). The entire open reading frame of the DJ-1 gene was screened by direct sequencing in 185 unrelated YOPD patients and a...

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Source

Identifiers

PMID: 12953260
DOI: 10.1002/ana.10675

Genes

PARK7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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