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Article

Genotypic and phenotypic characteristics of Dutch patients with early onset Parkinson's disease.

Movement disorders : official journal of the Movement Disorder Society - 30 Jan 2009

Macedo Maria G, Verbaan Dagmar, Fang Yue, van Rooden Stephanie M, Visser Martine, Anar Burcu, Uras Antonella, Groen Justus L, Rizzu Patrizia, van Hilten Jacobus J, Heutink Peter

Abstract excerpt

Early onset Parkinson's disease (EOPD) has been associated with mutations in the Parkin, DJ-1, PINK1, LRRK2, and SNCA genes. The aim of this study is to assess the contribution of these genes in a Dutch EOPD cohort and the phenotypic characteristics of the mutation carriers. A total of 187 unrelated Dutch EOPD patients (age at onset < or = 50 years) were phenotyped and screened for mutations in all exons of...

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Source

Identifiers

PMID: 18973254
DOI: 10.1002/mds.22287

Genes

PINK1
SNCA

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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