Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DJ-1 (PARK7) mutations are less frequent than Parkin (PARK2) mutations in early-onset Parkinson disease.

Neurology - 10 Feb 2004

Hedrich K, Djarmati A, Schäfer N, Hering R, Wellenbrock C, Weiss P H, Hilker R, Vieregge P, Ozelius L J, Heutink P, Bonifati V, Schwinger E, Lang A E, Noth J, Bressman S B, Pramstaller P P, Riess O, Klein C

Abstract excerpt

BACKGROUND: Mutations in the Parkin gene (PARK2) are the most commonly identified cause of recessively inherited early-onset Parkinson disease (EOPD) but account for only a portion of cases. DJ-1 (PARK7) was recently reported as a second gene associated with recessively inherited PD with a homozy...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset
Share to Intracellular Signaling Peptides and Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Introns

Share to Oncogene Proteins

Share to Parkinson Disease

Share to Protein Deglycase DJ-1

Share to RNA Splice Sites

Share to Sequence Deletion

Source

Identifiers

PMID: 14872018
DOI: 10.1212/01.wnl.0000113022.51739.88

Genes

PARK7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14872018-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DJ-1 (PARK7) mutations are less frequent than Parkin (PARK2) mutations in early-onset Parkinson disease.PMID 14872018Read ↗

Incidence of mutations in the PARK2, PINK1, PARK7 genes in Polish early-onset Parkinson disease patients.Semantic proximity Read ↗

Rare heterozygous parkin variants in French early-onset Parkinson disease patients and controlsSemantic proximity Read ↗

The role of pathogenic DJ-1 mutations in Parkinson's disease.Semantic proximity Read ↗

Case-control study of the parkin gene in early-onset Parkinson disease.Semantic proximity Read ↗

Early-onset Parkinson's disease caused by a compound heterozygous DJ-1 mutation.Semantic proximity Read ↗

Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism.Semantic proximity Read ↗

Screening for DJ-1 mutations in early onset autosomal recessive parkinsonism.Semantic proximity Read ↗

Early Onset Parkinson's disease due to DJ1 mutations: An Indian study.Semantic proximity Read ↗

A wide variety of mutations in the parkin gene are responsible for autosomal recessive parkinsonism in Europe. French Parkinson's Disease Genetics Study Group and the European Consortium on Genetic Susceptibility in Parkinson's Disease.Semantic proximity Read ↗

Detection of Parkin (PARK2) and DJ1 (PARK7) mutations in early-onset Parkinson disease: Parkin mutation frequency depends on ethnic origin of patients.Semantic proximity Read ↗

Heterozygosity for a mutation in the parkin gene leads to later onset Parkinson disease.Semantic proximity Read ↗

A novel homozygous DJ1 mutation causes parkinsonism and ALS in a Turkish family.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.