Article
Haplotype information and linkage disequilibrium mapping for single nucleotide polymorphisms.
Genome research - 1 Sept 2003
Lu Xin, Niu Tianhua, Liu Jun S
Abstract excerpt
Single nucleotide polymorphisms in the human genome have become an increasingly popular topic in that their analyses promise to be a key step toward personalized medicine. We investigate two related questions, how much the haplotype information contributes to linkage disequilibrium (LD) mapping and whether an in silico haplotype construction preceding the LD analysis can help. For disease gene mapping, using both...
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