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Article

Rate limiting factors in melanocortin 1 receptor signalling through the cAMP pathway.

Pigment cell research - 1 Oct 2003

Más Jesús Sánchez, Gerritsen Ineke, Hahmann Christa, Jiménez-Cervantes Celia, García-Borrón José Carlos

Abstract excerpt

The melanotropic actions of alpha-melanocyte-stimulating hormone (alpha-MSH) and other melanocortins are mediated by activation of the melanocortin 1 receptor (MC1R). This G protein-coupled receptor is positively coupled to Gs and triggers the cyclic adenosine mono-phosphate (cAMP) pathway. Mutations of the MC1R gene are associated with skin type and pigmentation phenotypes, and with increased risk of skin...

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Identifiers

PMID: 12950734
DOI: 10.1034/j.1600-0749.2003.00073.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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