Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Manipulation of human B cells to confer immortality.

Human antibodies and hybridomas - 1 Oct 1992

Jonak Z L, Henri E, Trulli S, Jensen C P, Muirhead K A

Abstract excerpt

Electroporation was used to deliver genomic DNA from a lymphoid tumor to activated/stimulated human peripheral blood lymphocytes to create immortalized lymphoid cell lines. Activation of the recipient lymphocytes was essential for efficient immortalization. A panel of human B cell transfectant clones, each phenotypically representing specific stages of differentiation, resulted from the transfection. Monoclonal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies, Monoclonal
Share to B-Lymphocytes
Share to Cell Differentiation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Line, Transformed

Share to Lymphocyte Activation

Share to Phenotype

Share to Transfection

Source

Identifiers

PMID: 1335787

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Manipulation of human B cells to confer immortality.PMID 1335787Read ↗

Conditional Immortalization of Human B Cells by CD40 LigationSemantic proximity Read ↗

Genetic manipulation and immortalized culture of ex vivo primary human germinal center B cellsSemantic proximity Read ↗

Immortalization of human lymphocytes by Epstein-Barr virus.Semantic proximity Read ↗

Stable long-term cultures of self-renewing B cells and their applications.Semantic proximity Read ↗

Immortalization and Transformation of Human CellsSemantic proximity Read ↗

Immortalization of human primary B lymphocytes in vitro with DNA.Semantic proximity Read ↗

Growth factor requirements and basal phenotype of an immortalized mammary epithelial cell line.Semantic proximity Read ↗

Comparative biology of cell immortalization.Semantic proximity Read ↗

Immortalized erythroid cells as a novel frontier for in vitro blood production: current approaches and potential clinical applicationSemantic proximity Read ↗

Immortalization of Human CD8+ T Cell Clones by Ectopic Expression of Telomerase Reverse TranscriptaseSemantic proximity Read ↗

Establishment of an Efficient Immortalization Strategy Using HMEJ-Based bTERT Insertion for Bovine CellsSemantic proximity Read ↗

An efficient method for the rapid establishment of Epstein‐Barr virus immortalization of human B lymphocytesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.