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Article

Evaluation of gene targeting by homologous recombination in ovine somatic cells.

Molecular reproduction and development - 1 Oct 2003

Williams Sarah H, Sahota Virender, Palmai-Pallag Timea, Tebbutt Scott J, Walker Jean, Harris Ann

Abstract excerpt

Mouse models for some human genetic diseases are limited in their applications since they do not accurately reproduce the phenotype of the human disease. It has been suggested that larger animals, for example sheep, might produce more useful models, as some aspects of sheep physiology and anatomy are more similar to those of humans. The development of methods to clone animals from somatic cells provides a...

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PMID: 12950098
DOI: 10.1002/mrd.10340

Genes

CFTR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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