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Article

Activated signal transducer and activator of transcription 3 (STAT3) supports the malignant phenotype of human pancreatic cancer.

Gastroenterology - 1 Sept 2003

Scholz Arne, Heinze Sandra, Detjen Katharina M, Peters Michael, Welzel Martina, Hauff Peter, Schirner Michael, Wiedenmann Bertram, Rosewicz Stefan

Abstract excerpt

BACKGROUND & AIMS: Constitutive activation of signal transducer and activator of transcription 3 (STAT3) has been implicated in regulation of growth and malignant transformation. We therefore analyzed the expression and biologic significance of STAT3 in human pancreatic cancer cells. METHODS: Expression and activation of STAT3 were investigated by immunohistochemistry and immunoblotting. Functional inactivation...

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Source

Identifiers

PMID: 12949733
DOI: 10.1016/s0016-5085(03)01064-3

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STAT3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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