Article
Tumor necrosis factor-alpha gene G308A polymorphism is associated with the risk of preterm delivery.
Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences - 1 Aug 2003
Chen Dafang, Hu Yonghua, Wu Baiyan, Chen Li, Fang Zhi'an, Yang Fan, Wang Lihua
Abstract excerpt
OBJECTIVE: To investigate the association between polymorphism in tumor necrosis factor-alpha(TNF-alpha)/G308A and preterm delivery (PTD). Between July 1999 and June 2001, we conducted a molecular epidemiological study on genetic determinants of PTD at Anqing Hospital, China. METHODS: In a case-control-parent triads study, we investigated a total of 133 nuclear families: 79 normal gestational age families and 54...
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