Article
Lys656Asn polymorphism of leptin receptor gene is related with leptin changes after a high monounsaturated fat diet in obese patients.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research - 1 Feb 2013
de Luis Daniel A, Aller Rocio, Izaola Olatz, Conde Rosa, Eiros Bouza Jose
Abstract excerpt
BACKGROUND: Human obesity is characterized by high levels of leptin, and it has been suggested that obese patients may be leptin resistant. The aim of our study was to investigate the influence of Lys656Asn polymorphism in the leptin receptor gene on metabolic response, weight loss, and serum leptin levels to a high monounsaturated fat hypocaloric diet in obese patients. DESIGN: A sample of 126 obese patients was...
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