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Article

The loop between helix 4 and helix 5 in the monocarboxylate transporter MCT1 is important for substrate selection and protein stability.

The Biochemical journal - 1 Dec 2003

Galić Sandra, Schneider Hans-Peter, Bröer Angelika, Deitmer Joachim W, Bröer Stefan

Abstract excerpt

Transport of lactate, pyruvate and the ketone bodies acetoacetate and beta-hydroxybutyrate, is mediated in most mammalian cells by members of the monocarboxylate transporter family (SLC16). A conserved signature sequence has been identified in this family, which is located in the loop between hel...

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Identifiers

PMID: 12946269
DOI: 10.1042/BJ20030799
PMCID: PMC1223779

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12946269-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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