Article
Modeling Neurodegenerative Disorders in Drosophila melanogaster.
International journal of molecular sciences - 26 Apr 2020
Bolus Harris, Crocker Kassi, Boekhoff-Falk Grace, Chtarbanova Stanislava
Abstract excerpt
Drosophila melanogaster provides a powerful genetic model system in which to investigate the molecular mechanisms underlying neurodegenerative diseases. In this review, we discuss recent progress in Drosophila modeling Alzheimer's Disease, Parkinson's Disease, Amyotrophic Lateral Sclerosis (ALS), Huntington's Disease, Ataxia Telangiectasia, and neurodegeneration related to mitochondrial dysfunction or traumatic...
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