Article
Ecm10p localizes in yeast mitochondrial nucleoids and its overexpression induces extensive mitochondrial DNA aggregations.
Biochemical and biophysical research communications - 12 Sept 2003
Sakasegawa Yuji, Hachiya Naomi S, Tsukita Shoichiro, Kaneko Kiyotoshi
Abstract excerpt
Ecm10p was initially identified as a cell wall synthesis-related gene product [Genetics 147 (1997) 435] and also reported as a mitochondrial protein which was partially capable of compensating the phenotypic defect by SSC1 gene mutation [FEBS Lett. 487 (2000) 307]. Here we report that ecm10p is localized in mitochondrial nucleoids as its major component and the targeting signal resides between amino acid residues...
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