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Article

Regulating the regulators: the role of nicotinic acetylcholine receptors in human epilepsy.

Drug news & perspectives - 1 Jun 2003

Hogg R C, Bertrand D

Abstract excerpt

Recent advances in genetic mapping have linked several epilepsies to mutations in genes coding for ion channel proteins. Mutations in genes coding for the alpha(4) and beta(2) subunits of the nicotinic acetylcholine receptor have been found in some families suffering from autosomal dominant nocturnal frontal lobe epilepsy. Expression of mutant alleles in the Xenopus oocyte expression system has allowed functional...

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Identifiers

PMID: 12942156
DOI: 10.1358/dnp.2003.16.5.829313

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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