Article
Neuronal nicotinic acetylcholine receptors: their properties and alterations in autosomal dominant nocturnal frontal lobe epilepsy.
Revue neurologique - 1 Jul 1999
Bertrand D
Abstract excerpt
Identification of genes coding for the neuronal nicotinic acetylcholine receptors (nAChRs) has allowed rapid progress in the field of neuroscience. Determination of a high-affinity binding site for nicotine that correlates with the expression of mRNAs coding for nAChRs as well as protein expression is the best demonstration for localization of these receptors. Reconstitution of functional nAChRs in cells...
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