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A genetic variant in SLC6A20 is associated with Type 2 diabetes in white-European and Chinese populations.

Diabetic medicine : a journal of the British Diabetic Association - 1 Nov 2014

Ling Y, van Herpt T T W, van Hoek M, Dehghan A, Hofman A, Uitterlinden A G, Jiang S, Lieverse A G, Bravenboer B, Lu D, van Duijn C M, Gao X, Sijbrands E J G

Abstract excerpt

AIMS: To investigate whether polymorphisms in SLC6A20 are associated with susceptibility to Type 2 diabetes. METHODS: In the Rotterdam Study, a prospective, population-based cohort (n = 5974), 22 tagging polymorphisms with minor allele frequencies>0.05 across SLC6A20 were studied. Replication studies were performed in an independent Dutch case-control study (DiaGene-Rotterdam Study 2 n = 3133), and in a Chinese...

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PMID: 24958070
DOI: 10.1111/dme.12528

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