Article
HLA is a candidate region for psoriatic arthritis. evidence for excessive HLA sharing in sibling pairs.
Human immunology - 1 Sept 2003
Gladman Dafna D, Farewell Vernon T, Pellett Fawnda, Schentag Cathy, Rahman Proton
Abstract excerpt
Psoriatic arthritis (PsA) is an inflammatory arthritis that may affect as many as 30% of patients with psoriasis (Ps). Genetic factors play an important role in the susceptibility to and the expression of PsA. The objective of this study was to identify whether haplotype sharing among affected sibling pairs of individuals with PsA is increased compared with unaffected sibling pairs. We collected 182 sibling pairs...
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