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Article

Evidence of a substantial genetic basis for IgG2 levels in families with aggressive periodontitis.

Journal of dental research - 1 Sept 2003

Diehl S R, Wu T, Burmeister J A, Califano J V, Brooks C N, Tew J G, Schenkein H A

Abstract excerpt

IgG2 is elevated in localized but not in generalized aggressive periodontitis (AgP). Exposure to pathogenic bacteria is essential for disease. Immune responses are dominated by IgG2 reactive with bacterial surface carbohydrates. We used variance component analyses to assess IgG2 heritability and...

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Identifiers

PMID: 12939355
DOI: 10.1177/154405910308200910

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12939355-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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Evidence of a substantial genetic basis for IgG2 levels in families with aggressive periodontitis.PMID 12939355Read ↗

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