Article
GWAS of Serum Antibodies to Microbial Biomarker Species of Periodontitis.
Journal of dental research - 1 Jul 2026
Abdelkader H, Salminen A, Leskelä J, Palviainen T, Salasuo E, Paju S, Mäntylä P, Suominen L, Kaprio J, Salomaa V, Sinisalo J, Pussinen P J
Abstract excerpt
Serum antibody levels against microbial biomarkers of periodontitis, Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis, are associated especially with the presence of these species in the oral cavity. We investigated the genetic basis of host antibody responses against these species through a genome-wide association study (GWAS) to identify the genetic determinants of this immune reactivity....
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