Article
Enhanced prediction of lopinavir resistance from genotype by use of artificial neural networks.
The Journal of infectious diseases - 1 Sept 2003
Wang Dechao, Larder Brendan
Abstract excerpt
Our objective was to accurately predict, from complex mutation patterns, human immunodeficiency virus type 1 resistance to the protease inhibitor lopinavir, by use of artificial intelligence. Two neural network models were constructed: 1 based on changes at 11 positions in the protease that were...
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