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Article

Host defense and inflammatory gene polymorphisms are associated with outcomes after HLA-identical sibling bone marrow transplantation.

Blood - 1 Dec 2002

Rocha Vanderson, Franco Rendrik F, Porcher Raphael, Bittencourt Henrique, Silva Wilson A, Latouche Aurelien, Devergie Agnes, Esperou Helene, Ribaud Patricia, Socie Gerard, Zago Marco Antonio, Gluckman Eliane

Abstract excerpt

We made the hypothesis that donor and recipient gene polymorphisms that drive the host response to microorganisms could be associated with infections after bone marrow transplantation (BMT). HLA-identical BMT was performed for patients with acute (n = 39) or chronic leukemia (n = 68). Genotyping was performed in 107 D/R DNA pairs for gene polymorphisms of cytokines (tumor necrosis factor-alpha [TNF-alpha] and...

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Identifiers

PMID: 12393699
DOI: 10.1182/blood-2002-04-1033

Genes

MPO
TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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