Article
A novel yeast mutant that is defective in regulation of the Anaphase-Promoting Complex by the spindle damage checkpoint.
Molecular genetics and genomics : MGG - 1 Nov 2003
Lai L A, Morabito L, Holloway S L
Abstract excerpt
The accurate segregation of sister chromatids at the metaphase to anaphase transition in Saccharomyces cerevisiae is regulated by the activity of the anaphase-promoting complex or cyclosome (APC/C). In the event of spindle damage or monopolar spindle attachment, the spindle checkpoint is activate...
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