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Article

The ACE gene I/D polymorphism is not associated with the blood pressure and cardiovascular benefits of ACE inhibition.

Hypertension (Dallas, Tex. : 1979) - 1 Sept 2003

Harrap Stephen B, Tzourio Christophe, Cambien François, Poirier Odette, Raoux Segolene, Chalmers John, Chapman Neil, Colman Samuel, Leguennec Solenn, MacMahon Stephen, Neal Bruce, Ohkubo Takayoshi, Woodward Mark

Abstract excerpt

The insertion/deletion (I/D) polymorphism of the angiotensin-converting enzyme (ACE) gene might have consequences for the risks of vascular diseases. We examined the ACE genotype and the effects of a perindopril-based blood pressure-lowering regimen on macrovascular events, dementia, and cognitiv...

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Source

Identifiers

PMID: 12925557
DOI: 10.1161/01.HYP.0000088322.85804.96

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-12925557-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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The ACE gene I/D polymorphism is not associated with the blood pressure and cardiovascular benefits of ACE inhibition.PMID 12925557Read ↗

<i>ACE</i> Gene Polymorphism in Cardiovascular DiseaseSemantic proximity Read ↗

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Prospective evaluation of the angiotensin-converting enzyme insertion/deletion polymorphism and the risk of stroke.Semantic proximity Read ↗

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