Article
Gene expression profile of normal lungs predicts genetic predisposition to lung cancer in mice.
Carcinogenesis - 1 Nov 2003
Gariboldi Manuela, Spinola Monica, Milani Silvano, Pignatiello Carmen, Kadota Koji, Bono Hidemasa, Hayashizaki Yoshihide, Dragani Tommaso A, Okazaki Yasushi
Abstract excerpt
Genetic susceptibility to lung tumorigenesis shows large variations among mouse strains. To test whether genetic predisposition to lung tumorigenesis is associated with a specific gene expression profile in normal lungs, we analyzed gene expression in 16 inbred strains of known susceptibility/res...
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