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Article

Isolation and characterization of human esophageal microvascular endothelial cells: mechanisms of inflammatory activation.

American journal of physiology. Gastrointestinal and liver physiology - 1 Dec 2003

Rafiee Parvaneh, Ogawa Hitoshi, Heidemann Jan, Li Mona S, Aslam Mohammed, Lamirand Thomas H, Fisher Pamela J, Graewin Shannon J, Dwinell Michael B, Johnson Christopher P, Shaker Reza, Binion David G

Abstract excerpt

Gastroesophageal reflux disease is the most common malady of the esophagus, affecting 7% of the United States population. Histological assessment demonstrates classic inflammatory mechanisms including selective leukocyte recruitment and hemorrhage, suggesting a prominent role for the microvasculature. We isolated and characterized human esophageal microvascular endothelial cells (EC) (HEMEC), examined...

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PMID: 12919942
DOI: 10.1152/ajpgi.00484.2002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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