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Article

Combined activities of hedgehog signaling inhibitors regulate pancreas development.

Development (Cambridge, England) - 1 Oct 2003

Kawahira Hiroshi, Ma Nancy H, Tzanakakis Emmanouhl S, McMahon Andrew P, Chuang Pao-Tien, Hebrok Matthias

Abstract excerpt

Hedgehog signaling is known to regulate tissue morphogenesis and cell differentiation in a dose-dependent manner. Loss of Indian hedgehog (Ihh) results in reduction in pancreas size, indicating a requirement for hedgehog signaling during pancreas development. By contrast, ectopic expression of so...

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Identifiers

PMID: 12917290
DOI: 10.1242/dev.00653

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12917290-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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