Article
Genetics of hypertension: lessons learnt from mendelian and polygenic syndromes.
Clinical and experimental hypertension (New York, N.Y. : 1993) - 1 Jan 2000
Dominiczak Anna F, Brain Nick, Charchar Fadi, McBride Martin, Hanlon Neil, Lee Wai Kwong
Abstract excerpt
This brief review discusses genetic and genomic aspects of hypertension. A special emphasis is given to currently available strategies for gene identifications, including studies of rare Mendelian hypertension, candidate gene evaluation, genome-wide scans and approaches based on the comparative genome analysis. We also discuss the growing potential for pharmacogenetic approaches and address briefly the issue of...
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