Platelet storage pool deficiency, leukemia, and myelodysplastic syndromes.

doi:10.3109/10428199209051007

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Article

Platelet storage pool deficiency, leukemia, and myelodysplastic syndromes.

Leukemia & lymphoma - 1 Nov 1992

Gerrard J M, McNicol A

Abstract excerpt

Abnormalities in platelet dense granules, small intracellular organelles containing ATP, ADP, calcium, serotonin, and pyrophosphate, have frequently been reported in patients with leukemia and myeloproliferative disorders, particularly acute and chronic myelogenous leukemia. Recent studies of a family which includes several members with an autosomal dominant dense granule deficiency condition show an association...

Topics

Adult
Aged
Blood Platelets
Child
Child, Preschool
Chromosome Aberrations
Chromosomes, Human, Pair 7
Cytoplasmic Granules
Female
Genes, Dominant
Genetic Predisposition to Disease
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Infant

Leukemia, Myeloid, Acute

Male

Megakaryocytes

Membrane Proteins

Middle Aged

Source

Open in PubMed

Identifiers

PMID: 1290957
DOI: 10.3109/10428199209051007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1290957-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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