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Article

Heparin-induced substrate behavior of antithrombin Cambridge II.

Blood - 1 Dec 2003

Mushunje Alec, Zhou Aiwu, Carrell Robin W, Huntington James A

Abstract excerpt

Cambridge II (A384S) is a highly prevalent antithrombin variant in the British population (1.14 per 1000) and predisposes carriers to a mild but significant increased risk of thrombosis. To determine if the association of Cambridge II with thrombophilia is due to a perturbation of the antithrombin inhibitory mechanism, we expressed and characterized the variant. Antithrombin Cambridge II was found to be normal in...

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Source

Identifiers

PMID: 12907439
DOI: 10.1182/blood-2003-05-1560

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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