Article
Recombinant-inbred strains: general methodological considerations relevant to the study of complex characters.
Behavior genetics - 1 Nov 1992
Blizard D A
Abstract excerpt
If appropriately determined, recombinant-inbred (RI) strain means provide an excellent method for determining genetic correlations among complex characters. However, little systematic attention has been paid to important environmental influences on strain means such as random effects due to litter membership or systematic maternal influences, which are inevitably confounded with genetic effects. It is suggested...
Topics
- Animals
- Behavior, Animal
- Chromosome Mapping
- Mice
- Mice, Inbred Strains
- Models, Genetic
- Phenotype
- Recombination, Genetic
- Social Environment