Collagen-induced rat platelet reactivity is enhanced in whole blood in both the presence and absence of dense granule secretion.

doi:10.1016/0049-3848(92)90093-p

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Article

Collagen-induced rat platelet reactivity is enhanced in whole blood in both the presence and absence of dense granule secretion.

Thrombosis research - 1 Dec 1992

Magro A, Bizios R, Catalfamo J, Blumenstock F, Rudofsky U

Abstract excerpt

Collagen induced aggregation, ATP secretion and thromboxane (TxB2) generation of storage pool deficient platelets were compared to normal platelets of closely related rat strains. Platelet function was monitored in citrated-platelet-rich-plasma (PRP) and citrated whole blood. Wistar (W) and fawn-hooded (FH) rat strains and their F2 hybrids were utilized. The W strain, which is ancestral to the FH strain, is not...

Topics

Adenosine Triphosphate
Animals
Blood Platelets
Collagen
Genotype
Male
Platelet Aggregation
Platelet Storage Pool Deficiency
Rats
Rats, Inbred Strains
Rats, Wistar

Thromboxane A2

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