Thromboxane responsiveness of dog platelets is inherited as an autosomal recessive trait.

Article

Thromboxane responsiveness of dog platelets is inherited as an autosomal recessive trait.

Thrombosis and haemostasis - 6 May 1991

Johnson G J, Leis L A, King R A

Abstract excerpt

Most mongrel dogs have platelets that form thromboxane A2 (TXA2) from exogenous arachidonate, but they fail to aggregate or secrete in response to it. In contrast to these TXA2 insensitive (TXA2-) platelets, some dogs have TXA2 sensitive (TXA2+) platelets that aggregate and secrete when stirred w...

Topics

Aging
Animals
Blood Platelets
Dogs
Female
Genes, Recessive
Male
Pedigree
Phenotype
Platelet Aggregation
Serotonin
Thromboxane A2

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