Article
Thromboxane responsiveness of dog platelets is inherited as an autosomal recessive trait.
Thrombosis and haemostasis - 6 May 1991
Johnson G J, Leis L A, King R A
Abstract excerpt
Most mongrel dogs have platelets that form thromboxane A2 (TXA2) from exogenous arachidonate, but they fail to aggregate or secrete in response to it. In contrast to these TXA2 insensitive (TXA2-) platelets, some dogs have TXA2 sensitive (TXA2+) platelets that aggregate and secrete when stirred with arachidonate. To evaluate the possible genetic basis for this difference, we carried out seven matings of mongrel...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.