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Article

Natural variation in populations of persistently colonizing bacteria affect human host cell phenotype.

The Journal of infectious diseases - 15 Aug 2003

Aras Rahul A, Lee Yongchan, Kim Sung-Kook, Israel Dawn, Peek Richard M, Blaser Martin J

Abstract excerpt

The highly diverse bacterium Helicobacter pylori, which persistently colonizes the human stomach, provides models to study the role of genome plasticity in host adaptation. Within H. pylori populations from 2 colonized individuals, intragenomic recombination between cagA DNA repeat sequences leads to deletion or duplication of tyrosine phosphorylation sites in the CagA protein, which is injected by a type IV...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 12898434
DOI: 10.1086/377098

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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