Article
Genetic analysis of ryanodine receptor function in Caenorhabditis elegans based on unc-68 revertants.
Molecular genetics and genomics : MGG - 1 Sept 2003
Adachi R, Kagawa H
Abstract excerpt
The Caenorhabditis elegans ryanodine receptor is encoded by the unc-68 gene, and functions as a Ca2+-induced Ca2+ release channel during muscle contraction. To investigate the factors that suppress calcium release and identify molecules that interact with the ryanodine receptor, we isolated revertants from two unc-68 mutants. Three of the revertants obtained from the null allele unc-68(e540), which displayed...
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